Product Overview
dMCL1-2 | T13657 | TargetMol Chemicals
CAS: 2351218-88-5
Smiles: CN(C)S(=O)(=O)N1CCN(CC1)c1ccc(OCc2c(c(C)nn2C)-c2cccc3c(CCCOc4cccc5ccccc45)c(C(O)=O)n(CCN4CCN(CC4)C(=O)COc4cccc5C(=O)N(C6CCC(=O)NC6=O)C(=O)c45)c23)cc1
Formula: C61H66N10O12S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: dMCL1-2 is a potent and selective myeloid leukemia 1 (MCL1) degrading agent based on PROTAC, which binds to MCL1 with a KD of 30 nM. dmcl-2 activates the apoptosis mechanism by degrading MCL1.
Molecular Weight: 1163, 32
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