Product Overview
1, 2, 3, 4, 5, 6-Hexabromocyclohexane | T22462 | TargetMol Chemicals
CAS: 1837-91-8
Smiles: BrC1C(Br)C(Br)C(Br)C(Br)C1Br
Formula: C6H6Br6
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: The compound effectively and directly inhibits JAK2 tyrosine kinase autophosphorylation and specifically inhibits ligand-dependent JAK2 activation. It has no cytotoxicity at 100 μM. A 16-hour treatment with compound (1 μM) decreases JAK2 tyrosine autophosphorylation levels to ~ 50% while 50 μM eliminates nearly all JAK2 activity.
Molecular Weight: 557, 538
![4-[(E)-{[4, 6-Di(4-morpholinyl)-1, 3, 5-triazin-2-yl]hydrazono}methy l]-2, 6-dimethoxyphenol](https://cdn11.bigcommerce.com/s-2kvb5rm600/images/stencil/500x659/products/47155/43811/TargetMol-768x384__12443.1665998863__35056.1666031504.png?c=1 "4-[(E)-{[4, 6-Di(4-morpholinyl)-1, 3, 5-triazin-2-yl]hydrazono}methy l]-2, 6-dimethoxyphenol")
![5-(5-methyl-1H-1, 2, 4-triazol-3-yl)-3-[4-(trifluoromethoxy)phenyl]-1, 2, 4-oxadiazole](https://cdn11.bigcommerce.com/s-2kvb5rm600/images/stencil/500x659/products/43875/40531/TargetMol-768x384__12443.1665998863__16175.1666026886.png?c=1 "5-(5-methyl-1H-1, 2, 4-triazol-3-yl)-3-[4-(trifluoromethoxy)phenyl]-1, 2, 4-oxadiazole")
