Product Overview
11R-VIVIT | TP1978 | TargetMol Chemicals
CAS: 592517-80-1
Smiles:
Formula: C147H259N67O36S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: NFAT inhibitor. Inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. Improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. Cell permeable.
Molecular Weight: 3573, 15
