Product Overview
12-O-Methylcarnosic acid | TN2601 | TargetMol Chemicals
CAS: 62201-71-2
Smiles: [H][C@@]12CCc3cc(C(C)C)c(OC)c(O)c3[C@]1(CCCC2(C)C)C(O)=O
Formula: C21H30O4
Pathway: Endocrinology/Hormones|||Metabolism
Target: Reductase
Receptor: N/A
Bioactivity: 12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM.12-O-Methylcarnosic acid has antioxidant activity, it is effective preventing gastric lesions. 12-O-Methylcarnosic acid can suppress melanin production with downregulation of tyrosinase expression in HMV-II melanoma cells.12-O-Methylcarnosic acid may have anti-diabetic activity, it is able to significantly activate peroxisome proliferator-activated receptor (PPAR)γ.
Molecular Weight: 346, 467
