Product Overview
18-Methoxycoronaridine | T26377 | TargetMol Chemicals
CAS: 308123-60-6
Smiles: [H][C@@]12[C@@H](CCOC)C[C@H]3CN1CCc1c([nH]c4ccccc14)[C@@]2(C3)C(=O)OC
Formula: C22H28N2O3
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: 18-Methoxycoronaridine is a nicotinic α3β4 antagonist. 18-Methoxycoronaridine slows the rate of induction of behavioral sensitization to nicotine. 18-MC inhibits α3β4 nicotinic acetylcholine receptors which are densely expressed in the medial habenula and interpeduncular nucleus. 18-Methoxycoronaridine also attenuates sucrose reward, decrease sucrose intake and prevent the development of sucrose-induced obesity.
Molecular Weight: 368, 477
