2-Methoxyestradiol | T2220

(No reviews yet) Write a Review
€170.00 - €294.00
SKU:
TMC-T2220
Availability:
IN STOCK
Adding to cart… The item has been added

Product Overview

2-Methoxyestradiol | T2220 | TargetMol Chemicals

CAS: 362-07-2

Smiles: c1c(c(cc2CC[C@H]3[C@@H]4CC[C@@H]([C@]4(CC[C@@H]3c12)C)O)O)OC

Formula: C19H26O3

Pathway: Angiogenesis|||Apoptosis|||Autophagy|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||Immunology/Inflammation|||Metabolism|||NF-Κb

Target: Apoptosis|||Reactive Oxygen Species|||Microtubule Associated|||Endogenous Metabolite|||HIF|||Autophagy

Receptor: N/A

Bioactivity: 2-Methoxyestradiol is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endothelial cell apoptosis. This agent also inhibits tumor cell growth by binding to tubulin, resulting in antimitotic activity, and by inducing caspase activation, resulting in cell cycle arrest in the G2 phase, DNA fragmentation, and apoptosis.

Molecular Weight: 302, 41

Reviews

(No reviews yet) Write a Review