Product Overview
3', 4', 5', 5, 7-Pentamethoxyflavone | T2A2486 | TargetMol Chemicals
CAS: 53350-26-8
Smiles: COc1cc(OC)c2c(c1)oc(cc2=O)-c1cc(OC)c(OC)c(OC)c1
Formula: C20H20O7
Pathway: Apoptosis|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Immunology/Inflammation|||Membrane transporter/Ion channel|||Neuroscience|||Proteases/Proteasome
Target: BCL|||PARP|||Caspase|||Nrf2|||P-gp
Receptor: N/A
Bioactivity: 3', 4', 5', 5, 7-Pentamethoxyflavone has anti-inflammatory and cancer chemopreventive activities. 3', 4', 5', 5, 7-Pentamethoxyflavone could be used as an effective adjuvant sensitizer to increase the efficacy of chemotherapeutic drugs by downregulating Nrf2 signaling pathway, it sensitizes Cisplatin-resistant A549 cells to Cisplatin by inhibition of Nrf2 pathway.
Molecular Weight: 372, 4
