3', 5, 5', 7-Tetrahydroxy-4', 6-dimethoxyflavone | TN5133

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€486.00
SKU:
TMC-TN5133
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Product Overview

3', 5, 5', 7-Tetrahydroxy-4', 6-dimethoxyflavone | TN5133 | TargetMol Chemicals

CAS: 125537-92-0

Smiles: COc1c(O)cc(cc1O)-c1cc(=O)c2c(O)c(OC)c(O)cc2o1

Formula: C17H14O8

Pathway: DNA Damage/DNA Repair|||Microbiology/Virology|||Proteases/Proteasome

Target: HIV Protease|||Topoisomerase

Receptor: N/A

Bioactivity: 5, 7, 3', 5'-tetrahydroxy-6, 4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev)MC99 virus and 1A2 cell line system, it shows considerably activity against HIV-1 reverse transcriptase. It exhibits cytotoxic activity against P-388 cell lines, it can inhibit DNA topoisomerase IIα activity, which may be responsible for the observed cytotoxicity.

Molecular Weight: 346, 3

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