3'-Hydroxypterostilbene | T2S2382

3'-Hydroxypterostilbene | T2S2382 | TargetMol Chemicals

CAS: 475231-21-1

Smiles: COc1cc(OC)cc(\C=C\c2ccc(O)c(O)c2)c1

Formula: C16H16O4

Pathway: Apoptosis|||Autophagy

Target: Apoptosis|||Autophagy

Receptor: N/A

Bioactivity: 3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively, by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the p38MAPK, and PI3K/Akt/mTOR/p70S6K pathways and activates the ERK1/2, JNK1/2 MAPK pathways[1].

Molecular Weight: 272, 3