3-Isomangostin | T2S1635

3-Isomangostin | T2S1635 | TargetMol Chemicals

CAS: 19275-46-8

Smiles:

Formula: C24H26O6

Pathway: DNA Damage/DNA Repair

Target: MTH1

Receptor: N/A

Bioactivity: 3-Isomangostin is an acetylcholinesterase selective inhibitor and a potent human aldose reductase inhibitor with an IC50 of 3.48 uM. 3-Isomangostin has free radical scavenging activity and inhibits MutT homolog 1 (MTH1) with an IC50 of 52 nM. It shows antiplasmodial activity with an IC50 values in the range of 4.71-11.40 uM. 3-Isomangostin can be used to develop anticancer agents as well.

Molecular Weight: 410, 46