Product Overview
3-MATIDA | T3486 | TargetMol Chemicals
CAS: 518357-51-2
Smiles: Cc1cc(sc1C(N)C(O)=O)C(O)=O
Formula: C8H9NO4S
Pathway: Neuroscience
Target: GluR|||NMDAR
Receptor: N/A
Bioactivity: 3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM). 3-MATIDA act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro.
Molecular Weight: 215, 22
