Product Overview
3-O-Methylgallic acid | TN1237 | TargetMol Chemicals
CAS: 3934-84-7
Smiles: COc1cc(cc(O)c1O)C(O)=O
Formula: C8H8O5
Pathway: Apoptosis|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||JAK/STAT signaling|||Membrane transporter/Ion channel|||NF-Κb|||Stem Cells
Target: Apoptosis|||NF-κB|||OCT|||DNA/RNA Synthesis|||STAT
Receptor: N/A
Bioactivity: 3, 4-Dihydroxy-5-methoxybenzoic acid reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3, 4-Dihydroxy-5-methoxybenzoic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer.
Molecular Weight: 184, 147
