Product Overview
4-CPPC | T38293 | TargetMol Chemicals
CAS: 29553-70-6
Smiles: OC(=O)c1cccc(c1)-c1cc(ncc1C(O)=O)C(O)=O
Formula: C14H9NO6
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: 4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).1It is selective for MIF-2 over MIF-1 (IC50= 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Molecular Weight: 287, 227
