Product Overview
4E1rcat | T1742 | TargetMol Chemicals
CAS: 328998-25-0
Smiles: OC(=O)c1ccc(cc1)N1C(=O)\C(=C/c2ccc(o2)-c2ccc(cc2)[N+]([O-])=O)C=C1c1ccccc1
Formula: C28H18N2O6
Pathway: Apoptosis|||Autophagy
Target: PERK|||Autophagy
Receptor: N/A
Bioactivity: 4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.
Molecular Weight: 478, 46