Product Overview
5, 7-Dihydroxychromone | T5S1805 | TargetMol Chemicals
CAS: 31721-94-5
Smiles: Oc1cc(O)c2c(c1)occc2=O
Formula: C9H6O4
Pathway: Apoptosis|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Immunology/Inflammation|||Microbiology/Virology|||Others|||Proteases/Proteasome
Target: Others|||Virus Protease|||PARP|||Caspase|||Nrf2
Receptor: N/A
Bioactivity: 1. 5, 7-Dihydroxychromone isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5, 7-Dihydroxychromone exerts neuroprotective effect against 6-OHDA-induced oxidative stress and apoptosis by activating Nrf2/ARE signal . 3. 5, 7-Dihydroxychromone induces the translocation of Nrf2 to the nucleus and increases Nrf2/ARE binding activity which results in the up-regulation of the expression of Nrf2-dependent antioxidant genes, including HO-1, NQO1, and GCLc.
Molecular Weight: 178, 143
