Product Overview
5Z-7-Oxozeaenol | T14055 | TargetMol Chemicals
CAS: 253863-19-3
Smiles: COc1cc(O)c2c(c1)\C=C\C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC2=O
Formula: C19H22O7
Pathway: Angiogenesis|||MAPK|||Microbiology/Virology|||Tyrosine Kinase/Adaptors
Target: VEGFR|||FLT|||MEK|||MAPK|||PDGFR|||Antibiotic|||Src
Receptor: N/A
Bioactivity: 5Z-7-Oxozeaenol is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is also an inhibitor of VEGF-R2 with IC50 of 52 nM.
Molecular Weight: 362, 378
