Product Overview
6-Deoxyjacareubin | TN3161 | TargetMol Chemicals
CAS: 16265-56-8
Smiles: CC1(C)Oc2cc3oc4c(O)cccc4c(=O)c3c(O)c2C=C1
Formula: C18H14O5
Pathway: GPCR/G Protein|||Microbiology/Virology
Target: PAFR|||Antifection
Receptor: N/A
Bioactivity: 6-Deoxyjacareubin possesses significant antioxidant activities, it also exhibits the cytotoxic activities against HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines.6-Deoxyjacareubin is antifungal against Cladosporium cucumerinum, while it shows differing degrees of inhibition of monoamine oxidase A and B. 6-Deoxyjacareubin shows strong platelet activating factor (PAF) receptor binding inhibitory effects using rabbit platelets with IC50 values of 29.0 microM, suggests that xanthones can represent a new class of natural PAF receptor antagonists.
Molecular Weight: 310, 3
