Product Overview
8alpha-Tigloyloxyhirsutinolide 13-O-acetate | TN3300 | TargetMol Chemicals
CAS: 83182-58-5
Smiles: C\C=C(/C)C(=O)O[C@H]1C[C@@H](C)[C@]2(O)CC[C@@](C)(O2)\C=C2\OC(=O)C(COC(C)=O)=C12
Formula: C22H28O8
Pathway: Immunology/Inflammation|||Metabolism|||Neuroscience
Target: NADPH-oxidase|||P450|||MAO
Receptor: N/A
Bioactivity: 8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has anti-cancer activity, it is active against both cancer cell lines (IC50 = 3.50 microM for HT29 and IC50 = 4.27 microM for HepG2).
Molecular Weight: 420, 45