Product Overview
9-Decyn-1-ol | T17346 | TargetMol Chemicals
CAS: 17643-36-6
Smiles: OCCCCCCCCC#C
Formula: C10H18O
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: 9-Decyn-1-ol is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. 9-Decyn-1-ol can be used to conjugate GDC-0068 with Lenalidomide to generate INY-03-041. INY-03-041 is a potent, highly selective and PROTAC-based pan-Akt degrader. INY-03-041 inhibits Akt1, Akt2 and Akt3 with IC50s of 2.0 nM, 6.8 nM and 3.5 nM, respectively[1].
Molecular Weight: 154, 253