Product Overview
A-1155463 | T6748 | TargetMol Chemicals
CAS: 1235034-55-5
Smiles: CN(C)CC#Cc1ccc(OCCCc2sc(nc2C(O)=O)N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)c(F)c1
Formula: C35H32FN5O4S2
Pathway: Apoptosis
Target: BCL
Receptor: N/A
Bioactivity: A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W(Ki=19 nM) and MCL-1(Ki>440 nM).
Molecular Weight: 669, 79
