Product Overview
A-3 hydrochloride | T14069 | TargetMol Chemicals
CAS: 78957-85-4
Smiles: Cl.NCCNS(=O)(=O)c1cccc2c(Cl)cccc12
Formula: C12H14Cl2N2O2S
Pathway: Chromatin/Epigenetic|||Cytoskeletal Signaling|||Metabolism|||Neuroscience|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: CaMK|||Casein Kinase|||PKA|||PKC
Receptor: N/A
Bioactivity: A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 μM and 80 μM, respectively[1]. A-3 hydrochloride against PKA (Ki=4.3 μM), casein kinase II (Ki=5.1 μM) and myosin light chain kinase (MLCK) (Ki=7.4 μM).
Molecular Weight: 321, 22
