Product Overview
A-366 | T3624 | TargetMol Chemicals
CAS: 1527503-11-2
Smiles: COc1cc2c(cc1OCCCN1CCCC1)N=C(N)C21CCC1
Formula: C19H27N3O2
Pathway: Chromatin/Epigenetic
Target: Epigenetic Reader Domain|||Histone Methyltransferase
Receptor: N/A
Bioactivity: Potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC50 = 3.3 nM). Exhibits >1000-fold selectivity for G9a/GLP over 21 other methyltransferases. Decreases levels of lysine 9 dimethylation on histone H3 (H3K9Me2) in PC3 cells.
Molecular Weight: 329, 444
