Product Overview
A-443654 | T14072 | TargetMol Chemicals
CAS: 552325-16-3
Smiles: N[C@H](COC1=CN=CC(C2=CC3=C(NN=C3C)C=C2)=C1)CC4=CNC5=CC=CC=C54
Formula: C24H23N5O
Pathway: Angiogenesis|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||MAPK|||Metabolism|||PI3K/Akt/mTOR signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: ERK|||VEGFR|||GSK-3|||FLT|||Casein Kinase|||MAPK|||Akt|||PKA|||Chk|||CDK|||Src|||PKC|||S6 Kinase
Receptor: N/A
Bioactivity: A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).
Molecular Weight: 397, 47
