Product Overview
A-674563 | T6139 | TargetMol Chemicals
CAS: 552325-73-2
Smiles: Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1
Formula: C22H22N4O
Pathway: Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||MAPK|||PI3K/Akt/mTOR signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: ERK|||GSK-3|||Akt|||PKA|||CDK
Receptor: N/A
Bioactivity: A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
Molecular Weight: 358, 445
