Product Overview
A-740003 | T3690 | TargetMol Chemicals
CAS: 861393-28-4
Smiles: COc1ccc(CC(=O)NC(N\C(Nc2cccc3ncccc23)=N\C#N)C(C)(C)C)cc1OC
Formula: C26H30N6O3
Pathway: Membrane transporter/Ion channel|||Neuroscience
Target: P2X Receptor|||P2 Receptor
Receptor: N/A
Bioactivity: A 740003 is an effective and specific P2X7 receptor antagonist (IC50: 18/40 nM, for rat/human). It can reduce nociception in animal models of persistent neuropathic and inflammatory pain, and also reduce neuroblastoma tumor growth in mice.
Molecular Weight: 474, 565
