Product Overview
A-770041 | T14074 | TargetMol Chemicals
CAS: 869748-10-7
Smiles: COc1cc(ccc1NC(=O)c1cc2ccccc2n1C)-c1nn([C@H]2CC[C@@H](CC2)N2CCN(CC2)C(C)=O)c2ncnc(N)c12
Formula: C34H39N9O3
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: Src
Receptor: N/A
Bioactivity: A-770041 is selective and orally active Src-family Lck inhibitor, and the other Src family kinase involved in T-cell signaling. A-770041 is a 147 nM inhibitor of Lck (1 mM ATP) and is 300-fold selective against Fyn, IC50 value: 147 nM Target: Lck.
Molecular Weight: 621, 746