Product Overview
A 80915A | T26450 | TargetMol Chemicals
CAS: 127875-60-9
Smiles: Cc1c(O)cc2C(=O)C3(CC4C(=C)CCC(Cl)C4(C)C)OC(C)(C)C(Cl)CC3(Cl)C(=O)c2c1O
Formula: C26H31Cl3O5
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: A 80915A is A semi-naphthoquinone antibiotic from Streptomyces aculeolatus. It is a potent inhibitor of gastric (H(+)-K+)-ATPase. Inhibition by A80915A is dependent on the conformation of gastric (H(+)-K+)-ATPase, potassium slows the rate of inhibition by converting the enzyme to a conformation where the drug binding site is not as accessible.
Molecular Weight: 529, 88