Product Overview
a-MSH, amide | TP2212 | TargetMol Chemicals
CAS: TP2212
Smiles: OC[C@]([H])(NC(=O)C)C(=O)N[C@]([H])(C/C1=C/C=C(/O)C=C1)C(=O)N[C@]([H])(CO)C(=O)N[C@]([H])(CC[S]C)C(=O)N[C@]([H])(CCC(O)=O)C(=O)N[C@]([H])(CC=2N=CNC=2)C(=O)N[C@]([H])(C/C3=C/C=CC=C3)C(=O)N[C@]([H])(CCCNC(N)=N)C(=O)N[C@]([H])(C/C4=C/NC=5C=CC=CC4=5)C(=O)NCC(=O)N[C@]([H])(CCCCN)C(=O)N6CCC[C@]6([H])C(=O)N[C@]([H])(C(N)=O)C(C)(C)[H]
Formula: C77H109N21O19S1
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: a-MSH, amide is a peptide with the sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2, MW= 1664.9. The melanocyte-stimulating hormones (collectively referred to as MSH or intermedins) are a class of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland. An increase in MSH will cause darkening in humans too. Melanocyte-stimulating hormone belongs to a group called the melanocortins. This group includes ACTH, alpha-melanocyte-stimulating hormone (α-MSH), (β-MSH), and (γ-MSH); these peptides are all cleavage products of a large precursor peptide called pro-opiomelanocortin (POMC). α-MSH is the most important melanocortin for pigmentation.
Molecular Weight: 1664, 9
