AAL-993 | T21593

AAL-993 | T21593 | TargetMol Chemicals

CAS: 269390-77-4

Smiles: FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1

Formula: N/A

Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors

Target: VEGFR

Receptor: N/A

Bioactivity: AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogenic and antitumor activities.

Molecular Weight: 371, 356