Product Overview
Abexinostat | T0431 | TargetMol Chemicals
CAS: 783355-60-2
Smiles: CN(C)Cc1c(oc2ccccc12)C(=O)NCCOc1ccc(cc1)C(=O)NO
Formula: C21H23N3O5
Pathway: Chromatin/Epigenetic|||DNA Damage/DNA Repair
Target: HDAC
Receptor: N/A
Bioactivity: PCI-24781 (Abexinostat) is a new pan-HDAC inhibitor mainly targeting HDAC1 (Ki: 7 nM), also have moderate inhibitory for HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.
Molecular Weight: 397, 431