Product Overview
ABT-737 | T2099 | TargetMol Chemicals
CAS: 852808-04-9
Smiles: CN(C)CC[C@H](CSc1ccccc1)Nc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1
Formula: C42H45ClN6O5S2
Pathway: Apoptosis|||Autophagy
Target: Mitophagy|||BCL|||Autophagy
Receptor: N/A
Bioactivity: ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w (EC50s: 78.7/30.3/197.8 nM).
Molecular Weight: 813, 43
