Product Overview
Acanthoic acid | T26545 | TargetMol Chemicals
CAS: 119290-87-8
Smiles: [H][C@@]12CC[C@]3([H])[C@@](C)(CCC[C@@]3(C)C1=CC[C@@](C)(C2)C=C)C(O)=O
Formula: C20H30O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Acanthoic acid is a pimaradiene diterpene isolated from Acanthopanax koreanum with anti-inflammatory activities. Acanthoic acid downregulates LPS-induced IL-1β, IL-6 and TNF-α production in BALF, attenuates lung histopathologic changes, and inhibits inflammatory cytokines by stopping IL-1β, IL-6 and TNF-α production and NF-κB activation in LPS-stimulated alveolar macrophages.
Molecular Weight: 302, 458