Acemetacin | T1467

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TMC-T1467
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Product Overview

Acemetacin | T1467 | TargetMol Chemicals

CAS: 53164-05-9

Smiles: COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCC(O)=O)c2c1

Formula: C21H18ClNO6

Pathway: Immunology/Inflammation|||Neuroscience

Target: COX

Receptor: N/A

Bioactivity: Acemetacin is a carboxymethyl ester of indometacin. It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin. In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin.

Molecular Weight: 415, 83

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