AcLys-PABC-VC-Aur0101 | T17357

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AcLys-PABC-VC-Aur0101 | T17357 | TargetMol Chemicals

CAS: 1438851-17-2

Smiles: CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)c1nccs1)OC)N(C)C(=O)[C@@H](NC(=O)C(C)(C)NC(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(C)=O)C(C)C)cc1)C(C)C

Formula: C66H103N13O13S

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: AcLys-PABC-VC-Aur0101 is a drug-linker conjugate for ADC (anti-CXCR4 ADC) with potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the cleavable linker AcLys-PABC-VC[1].

Molecular Weight: 1318, 69

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