Product Overview
Adagrasib | T8369 | TargetMol Chemicals
CAS: 2326521-71-3
Smiles: CN1CCC[C@H]1COc1nc2CN(CCc2c(n1)N1CCN([C@@H](CC#N)C1)C(=O)C(F)=C)c1cccc2cccc(Cl)c12
Formula: C32H35ClFN7O2
Pathway: GPCR/G Protein|||MAPK
Target: Ras
Receptor: N/A
Bioactivity: MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. It selectively modifies mutant cysteine 12 in GDP-bound KRASG12C, and inhibits KRAS-dependent signaling.
Molecular Weight: 604, 13