ADAMTS-5 Inhibitor | T14124

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TMC-T14124
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Product Overview

ADAMTS-5 Inhibitor | T14124 | TargetMol Chemicals

CAS: 929634-33-3

Smiles: Cn1nc(c(\C=C2/SC(=S)NC2=O)c1SCc1ccc(Cl)cc1)C(F)(F)F

Formula: C16H11ClF3N3OS3

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: ADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 μM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1)[1].

Molecular Weight: 449, 91

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