Product Overview
Adavosertib | T2077 | TargetMol Chemicals
CAS: 955365-80-7
Smiles: CN1CCN(CC1)c1ccc(Nc2ncc3c(n2)n(-c2cccc(n2)C(C)(C)O)n(CC=C)c3=O)cc1
Formula: C27H32N8O2
Pathway: Cell Cycle/Checkpoint
Target: Wee1
Receptor: N/A
Bioactivity: MK-1775 is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.
Molecular Weight: 500, 607
