Product Overview
Afuresertib hydrochloride | T7885 | TargetMol Chemicals
CAS: 1047645-82-8
Smiles: Cl.Cn1ncc(Cl)c1-c1cc(sc1Cl)C(=O)NC(CN)Cc1cccc(F)c1
Formula: C18H18Cl3FN4OS
Pathway: Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Stem Cells
Target: ROCK|||Akt|||PKC
Receptor: N/A
Bioactivity: Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
Molecular Weight: 463, 78