Product Overview
Afzelin | TN1362 | TargetMol Chemicals
CAS: 482-39-3
Smiles: C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)-c2ccc(O)cc2)[C@H](O)[C@H](O)[C@H]1O
Formula: C21H20O10
Pathway: Apoptosis|||Autophagy|||GPCR/G Protein|||Immunology/Inflammation|||MAPK|||Metabolism|||Microbiology/Virology|||PI3K/Akt/mTOR signaling
Target: PTEN|||p38 MAPK|||TNF|||Mitochondrial Metabolism|||Antibacterial|||Prostaglandin Receptor|||Autophagy
Receptor: N/A
Bioactivity: Afzelin has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absorbing activity and may protect human skin from UVB-induced damage by a combination of UV-absorbing and cellular activities. Afzelin attenuates the mitochondrial damage, enhances mitochondrial biogenesis and decreases the level of mitophagy-related proteins, parkin and PTEN-induced putative kinase 1.
Molecular Weight: 432, 381
