Product Overview
AG-7404 | T26574 | TargetMol Chemicals
CAS: 343565-99-1
Smiles: CCOC(=O)\C=C\[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC#C)n1cccc(NC(=O)c2cc(C)on2)c1=O
Formula: C26H29N5O7
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: AG-7404 is a potent protease inhibitor with anti-poliovirus activity. AG-7404 was active against all virus with EC50 values ranging from 0.080 to 0.674 μM. AG-7404 was fully active against V-073-resistant variants with EC50 values ranging from 0.218 to 0.819 μM, compared to values ranging from 0.202 to 0.407 μM for the V-073-susceptible parental strains.
Molecular Weight: 523, 546
