Product Overview
AG-825 | T14138 | TargetMol Chemicals
CAS: 149092-50-2
Smiles: COc1cc(\C=C(/C#N)C(N)=O)cc(CSc2nc3ccccc3s2)c1O
Formula: C19H15N3O3S2
Pathway: Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: EGFR
Receptor: N/A
Bioactivity: AG-825(Tyrphostin AG-825) is a potential agent for overcoming Mn-induced neurotoxicity or AD development[5] and is a selective and ATP-competitive ErbB2 inhibitor which suppresses tyrosine phosphorylation, with an IC50 of 0.35 μM. AG825 significantly accelerates apoptosis of human neutrophils[4]. AG-825 displays anti-cancer activity[1][2][3].
Molecular Weight: 397, 47
