Product Overview
AG311 | T26573 | TargetMol Chemicals
CAS: 1126602-42-3
Smiles: Cc1ccc(Sc2cccc3[nH]c4nc(N)nc(N)c4c23)cc1
Formula: C17H15N5S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: AG311 is an inhibitor of complex I and hypoxia-induced HIF-1α stabilization. In vitro, AG311 induces rapid necrosis in numerous cancer cell lines. Within minutes, exposure to AG311 also results in mitochondrial depolarization, superoxide production, and increased intracellular calcium levels.
Molecular Weight: 321, 4