Product Overview
AG490 | T2600 | TargetMol Chemicals
CAS: 133550-30-8
Smiles: Oc1ccc(\C=C(/C#N)C(=O)NCc2ccccc2)cc1O
Formula: C17H14N2O3
Pathway: Angiogenesis|||Autophagy|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: EGFR|||JAK|||STAT|||Autophagy
Receptor: N/A
Bioactivity: AG-490 (Tyrphostin AG 490) is an inhibitor of EGFR (IC50: 0.1 μM). It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src.
Molecular Weight: 294, 31
