Product Overview
Agerafenib hydrochloride | T14928 | TargetMol Chemicals
CAS: 1227678-26-3
Smiles: Cl.COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C(F)(F)F)c3)c2cc1OC
Formula: C24H23ClF3N5O5
Pathway: Apoptosis|||Tyrosine Kinase/Adaptors
Target: c-RET|||c-Kit
Receptor: N/A
Bioactivity: Agerafenib hydrochloride is a highly potent inhibitor of BRAFV600E (Kd: 14 nM).
Molecular Weight: 553, 92
