Product Overview
AK-1 | T5618 | TargetMol Chemicals
CAS: 330461-64-8
Smiles: [O-][N+](=O)c1cccc(NC(=O)c2cccc(c2)S(=O)(=O)N2CCCCCC2)c1
Formula: C19H21N3O5S
Pathway: Chromatin/Epigenetic|||DNA Damage/DNA Repair
Target: Sirtuin
Receptor: N/A
Bioactivity: AK-1 is a sirtuin 2 (SIRT2) inhibitor (IC50:12.5 μM).that prevents hippocampal neurodegeneration in Alzheimer's disease models and induces cell cycle arrest in colon carcinoma cells.
Molecular Weight: 403, 45