Product Overview
AK301 | T26585 | TargetMol Chemicals
CAS: 314022-97-4
Smiles: CCOc1ccccc1C(=O)N1CCN(CC1)c1cccc(Cl)c1
Formula: C19H21ClN2O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM). Colon cancer cells arrested in mitosis with AK301 readily underwent a p53-dependent apoptosis following compound withdrawal and arrest release.
Molecular Weight: 344, 84