Product Overview
AKOS-22 | T14150 | TargetMol Chemicals
CAS: 878983-38-1
Smiles: FC(F)(F)Oc1ccc(NC2CCN(CC2)C2CC(=O)N(C2=O)c2ccc(Cl)cc2)cc1
Formula: C22H21ClF3N3O3
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor (Kd=15.4 μM). AKOS-22 protects against mitochondrial dysfunction[1]. AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis.
Molecular Weight: 467, 87
