Product Overview
AKT inhibitor VIII | T3346 | TargetMol Chemicals
CAS: 612847-09-3
Smiles: O=c1[nH]c2ccccc2n1C1CCN(Cc2ccc(cc2)-c2nc3cc4[nH]cnc4cc3nc2-c2ccccc2)CC1
Formula: C34H29N7O
Pathway: Apoptosis|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||Akt
Receptor: N/A
Bioactivity: AKT inhibitor VIII is a highly specific Akt1/2 inhibitor (IC50: 58/210 nM). The selectivity for Akt1 is higher about 36-fold than Akt3.
Molecular Weight: 551, 654