Product Overview
Alendronate sodium | T22559 | TargetMol Chemicals
CAS: 129318-43-0
Smiles: C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.[Na+]
Formula: C4H12NNaO7P2
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: The compound binds and blocks farnesyl diphosphate synthase in the HMG-CoA pathway (IC50 = 460 nM for recombinant human FPPS). It causes macrophage apoptosis and inhibits prenylation and sterol biosynthesis in purified osteoclasts.
Molecular Weight: 271, 08
