Product Overview
Alisertib | T2241 | TargetMol Chemicals
CAS: 1028486-01-2
Smiles: COc1cc(Nc2ncc3CN=C(c4cc(Cl)ccc4-c3n2)c2c(F)cccc2OC)ccc1C(O)=O
Formula: C27H20ClFN4O4
Pathway: Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic
Target: Apoptosis|||Aurora Kinase|||Autophagy
Receptor: N/A
Bioactivity: Alisertib (MLN8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib is >200-fold higher for Aurora A than Aurora B.
Molecular Weight: 518, 93
